Relics

What Relics should I be investing into?
Prioritize unlocking new relics first. When you start needing more than 1 run to unlock a new relic, feel free to sprinkle some levels on whatever you feel is more useful short-term (usually monster stats such as Damage, Attack Speed, Crit Chance and Damage, Range, etc.).

Is it worth investing into upgrades that increase the amount of Prestige Points I get?
Usually not. The price of relics increases at a very fast rate, making it inefficient to rely on relics as the biggest way of progressing in the game.

What are Temporary Boosts?
Temporary Boosts are Boosts from the Relics System that last for your current prestige run. They reset and change after each prestige. Each boost slot (there are 4 of them) can potentially be one of four different boosts (ex. Game Speed can only be in the 4th Slot, while Crit Damage can only be in the 1st Slot). You upgrade these with Prestige Points, and if you are not satisfied with your roll of boosts, you can re-roll them for a modest fee of 100 Gems. You can find a list of all temporary relics, and what slot they can appear in, in the IMTD Public Data sheet.